Evaluation of the toxic potential of aspartame in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9

YASIR HASAN SIDDIQUE, Simmi Anjum, Rahul x, Smita Jyoti


Aspartame is commonly used as a sweetener in prepared foods, beverages and in recipes. In the present study the possible toxic effects of aspartame were studied in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. The third instar larvae were allowed to feed on the diet having different doses of aspartame. The results obtained in the present study suggest that the exposure of third instar larvae to the diet having 20, 40, 80, 160 and 320 mM of aspartame did not show any significant the toxic effects after 24 hours of the exposure compared to control (p<0.05). The results for pupae formation and emergence of flies also did not show any significant difference compared to control (p<0.05).


Aspartame; Drosophila melanogaster; toxicity.

Full Text:


This website is optimized for the last versions of Internet Explorer (V. 7 or higher) and Firefox. We therefore advise to download (or upgrade your internet browser to) IE 7 or Firefox. All rights reserved to The All Results Journals (c).

To help promote The All Results Journals:Biol (ISSN:2172-4784) you can now download our poster and display it in your library, common room, office or laboratory.